Revista Latinoamericana de Química


ABSTRACT

Rev. Latinoamer. Quím. 40, (1), 68-73, (2013)

ANALISIS DEL CONTENIDO ALCALOIDICO DE CALIPHRURIA SUBEDENTATA BAKER (AMARYLLIDACEAE)
POR EL METODO CG-EM

Fabio Cabezas1*, Natalia Pigni2, Jaume Bastida2, Carles Codina2 y Francesc Viladomat2

1 Departamento de Química. Grupo: Química de Compuestos Bioactivos, Facultad de Ciencias Naturales, Exactas y de la Eeducación. Universidad del Cauca. Calle 5 Nº 4-70. Popayán (Cauca), Colombia. 2 Departamento de Productos Naturales, Biología Vegetal y Edafología. Facultad de Farmacia. Universidad de Barcelona. Avenida Joan XXIII, 08028. Barcelona, España. *Autor para correspondencia: Fabio Cabezas: Tel. 0572-8209800 ext 2607. Fax 0572-8209860. E-mail.
facabz@unicauca.edu.co

Caliphruria is a genus of bulbous plants in the Amaryllidaceae family. It consists of four species distributed in tropical regions of South America, three of them are endemic of Colombia. This genus is infrequent in nature, with restricted geographical distribution. C. subedentata Baker is threatened by extinction. The polar extract showed moderate cytotoxic activity. In previews phytochemical studies, by classical methods, we isolated six alkaloids: galanthamine, lycorine, haemantamine, maritidine, homolycorine and hamayna. In this work we reports 18 compounds
identified by GC-MS technique: ismine, trisphaeridine, 5,6-dihydrobicolorine, galanthamine, clidantine, narwedine, kirkine, galantindol, maritidine, anhydrolycorine, deoxytazetine, 6-methoxypretazzetine, tazzetine, haemantamine, 11,12-dehydroanhydrolycorine, lycorine, homolycorine, epimacronine and one alkaloid not identified.www.relaquim.com

Key words: Alkaloids, galanthamine, lycorine, Caliphruria subedentata, Amaryllidaceae, GC-EM method, biological activity.

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